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THE TYLENOL GATE
PerpDex Wars Continue + Best Trader In The World + New Drake Meme?

Presented by Hype
Welcome to the HYPE TRAIN - a newsletter that breaks down what's happening in the crazy world of memecoins. We'll be breaking down the WTF moments, Best Trades, and much more, while trying to provide some humor to your day.
Disclaimer: Take none of this as financial advice & do your own research
Aaand here we go:
Pleasant day to be a degen! Welcome to today’s edition of Hype Train, where we will be covering our staples today:
TOP Memecoin Performances😇
PUMPFUN REBOUND!!!
TYLENOL GATE?!?!?! 😱
AND………………stories that will shake your head🙈
CRYPTO STAPLES🥇*As of 1:30 pm EST on September 22nd
Coin | Price | Market Cap | %Change(24hr) |
---|---|---|---|
$BTC | $112,551 | $2.2 Trillion | -2.5% |
$ETH | $4,178 | $504 Billion | -6.6% |
$SOL | $221.15 | $120 Billion | -6.6% |
HYPE INDEX🐐
$0.005960 | $2.1 Billion | -9.7% | |
$0.000002031 | $1.5 Billion | -10% | |
$7.60 | $1.5 Billion | -9.2% | |
$0.7896 | $789 Million | -11% | |
$0.6010 | $601 Million | -17.2% | |
$0.0000007403 | $289 Million | -12.9% | |
$0.2272 | $222 Million | -12.3% | |
$0.01053 | $101 Million | -6.3% | |
$0.01297 | $12.9 Million | -11.8% |
PERPDEX WARS CONTINUE🫡
Aster:
Aster ripped to ~$2.00 over the weekend (we shared it here at $0.80 cents). It has minted millionaires. It is able to differentiate from Hyperliquid by offering dark pools (private transactions) as well as higher leverage - you can go long/short up to 1001x. Since hitting ATH of $2.00 it has gotten jeeted to $1.40 as of now. The growth potential of perp DEXs / DEX's are massive - CZ himself believes that decentralized exchanges will completely disrupt centralized exchanges and ASTER is one of Binance's bets to have a horse in this race.
By community request, you can now long or short $HYPE with up to 300x leverage on Aster.
asterdex.com/en/futures/v1/…
Listing is not an endorsement of the project. Past performance does not guarantee future results. Do not trade assets you are unfamiliar with and do not understand
— Aster (@Aster_DEX)
1:58 PM • Sep 22, 2025
Avantis:
Avantis is another perp dex that is on Base (Coinbase's Layer 2). Their differentiator is no fees on losses, rebates, and focus on RWA (i.e. you can long/short US equities). Avantis ripped to $2.60 over the weekend - around a 2x from when we first mentioned it on Friday in the Hype News. Since then it has come down to $2.00
There are many $ASTER / $HYPE holders that are completely unaware about $AVNT (Avantis).
Do you understand how hard AVNT will pump?
Look at the LP-size.1. Backed by Base
2. Backed by Peter Thiel
3. Better FDV/MCAP ratio than Aster
4. No token-unlocks the coming 12 months— davidoff (@Z3KIMM)
6:04 PM • Sep 19, 2025
Hyperliquid:
With these new competitive perp dexes, Hyperliquid has dropped to $47.90. Arthur Hayes who was a Hyperliquid bull and had insane price targets for HYPE sold his position over the weekend. So did some other Hyperliquid whales.Other perp dexes too look out for in the coming future:
Lighter, which is also gaining market share.
Bullet.xyz - is a perp dex on Solana that is also set to launch in Q4.
It's getting competitive, but competition is a good thing. The winners of all of this will be the consumers !
Over the last few weeks, we've seen some PerpDEX tokens experiencing massive pumps.
Now everyone is looking for the next DEX to farm, but it seems like no one is looking among the DEXes that have been on the market for a while.
After analyzing numerous platforms, metrics,
— DC (@Pedr0_DC)
5:18 PM • Sep 18, 2025
TYLENOL GATE🗣
$0.0001615 | $161 Thousand | +1,609% |
Trump is set to announce that Tylenol use during pregnancy could be linked to autism, a claim that has already stirred controversy among scientists, doctors, and Tylenol’s parent company Kenvue, which insists decades of research show no causal connection and that acetaminophen remains one of the only safe pain relief options for expecting mothers. The announcement is scheduled with HHS Secretary Robert F. Kennedy Jr. and Dr Oz. $TYLENOL launched 16 days ago, but today’s news helped it rip 1,600% to a $161K market cap in a day under the banner of “Tylenol Gate.”
This is about to be the biggest story in the world tomorrow
$Tylenol
— Thomas (@Thomasthetank_)
1:16 AM • Sep 22, 2025
BEST TRADER ITW
$0.003584 | $3.5 Million | +26.5% |
The best trader in the world, Cupsey has had a token made for him since November, where it peaked candled at $20 Million. Cupsey’s wallet was drained recently, and he hasn’t lost his mojo according to the charts on printed.trade. Today, Cupsey token got an MEXC listing, and Alon tweeted in support, helping send $CUPSEY to a $3.5 Million market cap.
@CupseyToken thank you for your service @CupseyToken 🫡
— alon (@a1lon9)
3:20 PM • Sep 22, 2025
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That’s all for today’s edition, see you degens tomorrow!
DISCLAIMER: None of this is financial advice. This newsletter is strictly educational and is not investment advice or a solicitation to buy or sell any assets or to make any financial decisions. Please be careful and do your own research.